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, this list is not found in of cial market analyses or representative surveys): Inaccurate positioning technology Most of today s LBSs depend on Cell-Id positioning, which, as explained in 8, is easy and cheap to implement, but delivers only very inaccurate position xes with large variances More accurate positioning technologies like E-OTD or A-GPS are not deployed by most operators, unless they are required by law to do so, for example, to offer enhanced emergency services like E-911 The reason for the insuf cient implementation of advanced positioning results from the fact that in recent years most operators have tied up capital and manpower in the establishment of 3G networks and related multimedia services, and hence have neglected positioning and LBSs Less demand for data services in general Another reason for the moderate success of LBSs is the lack of demand for mobile data services in general.

5613 Antitumor Activity Some components of A annua L, such as qinghaosu (1), artemisinin B (10), artemisinic acid (20), artemisitene (26), avnoids, and other terpenoids, showed antitumor activities at varying concentrations against L-1210, P-388, A-549, HT-29, MCF-7, and KB in vitro69,254,255 In the assay of cytotoxicity of qinghaosu and related compounds against Ehrlich ascites tumor cells, qinghaosu, artemether, arteether, and artesunate exhibited cytotoxicity (IC50 122$298 mM), artemisitene 51 was more active (IC50 68 mM), and the dimer of dihydroartemisinin was the most potent (IC50 14 mM)256 258 The antitumor effect of artesunate was tested in vitro and in vivo in China259 261 It possessed cytotoxicity for six cell lines (IC50 1$100 mg/mL) and antitumor effects on human nasopharyngeal cancer (CNE2, SUNE-1) and human liver cancer (BEL-7402) in nude mice.

As indicated earlier, today s LBSs are almost always combined with data services such as a WAP browser or a client application, both executed on top of GPRS These services, when compared to the wired Internet, are often considered to be de cient because of insuf cient user interfaces, unsatisfactory bandwidth, and overpriced fees Thus, these negative attributes are also associated with LBSs On the other hand, the realization of voice or multimedia services as LBSs has not yet taken place..

Recently artesunate has been analyzed for its antitumor activity against 55 cell lines262 It was most active against leukemia and colon cancer cell lines It is notable that no CEM leukemia sublines, which are resistant to either doxorubicin, vincristine, methotrexate, or hydroxyurea, showed cross resistance to artesunate It was found that dihydroartemisinin can selectively kill cancer cells in the presence of holotransferrin, which can increase intracellular iron concentrations, and normal breast cells (HTB 125) and lymphocytes had nonsigni cant changes It seems the mechanisms of anticancer action and of antimalarial activity are similar263 265 The antitumor activity of N-glycoside, O-glycoside, and some dimers have been mentioned Recently, compound 153 was found to have antitumor activity.

It must be emphasized that, in general, it is not necessary to demodulate completely the transmit (terrestrial) baseband and the receive (satellite) baseband down to the telephone channel level, but only to select the multiplex equipment "building blocks" in order to interface the two sub-assemblies ("terrestrial multiplex" and "satellite multiplex") by the minimum number of supergroups, groups and/or telephone channels, as explained above. However, such an optimum design should remain flexible and should not preclude future extensions of the station traffic capacity.

where kr1 and kr2 are radial distortion coef cients; the sign of kr1 is positive for a barrel distortion and negative in the other case. Therefore, the projection model becomes y1 = c1 + f1 x1 + x2 and y2 = c2 + f2 x2. By assuming that = 0, we can write it in terms of the undistorted projection y plus the radial distortion terms y = y + ( y c ) [ kr1 r 2 + kr2 r 4 ] (2.5)

N F ((i + 1)h) ) n (ih) nk ((i + 1)h) = nk (ih) n jk (ih)h + F((i + 1)h) Fn (ih) Fj (ih) j =1

Additional study discovered the most active compound 154 in this series ( R p-Br, IC50 11 nM, and 27 nM against P 388 and A 549 cell lines, respectively), but its deoxy analog 155 is inactive266,267 Compound 156 yielded by coupling that the cyanoarylmethyl group with artesunate can not show higher antitumor activity than 154268 Flow cytometry data showed that these compounds caused an accumulation of L1210 and P388 cells in the G1-phase of the cell cycle and apoptosis in the P388 cells (Structure 5-24)266-268 More studies on antitumor action of qinghaosu analogs were reported269,270.

Add95: Art S9.11A (Res46) & Art S22.5A (Res115A) (not subject to S22.2)

This chapter describes many of the variables found in both the terminal and the shell environments. Linux supports three types of variables: